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update TFscanning_func function #65

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Merged
WWXkenmo merged 1 commit into from
Jan 13, 2026
Merged

update TFscanning_func function #65

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22 changes: 0 additions & 22 deletions src/regvelo/tools/_TFScanning_func.py
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Original file line number Diff line number Diff line change
Expand Up @@ -135,28 +135,6 @@ def TFScanning_func(
arr = np.array(fate_prob2.sum(0))
arr[arr != 0] = 1
fate_prob = fate_prob * arr

## intersection the states
terminal_states_perturb = g2.macrostates.cat.categories.tolist()
terminal_states_perturb = list(set(terminal_states_perturb).intersection(terminal_states))

g2.set_terminal_states(
terminal_states_perturb
)
g2.compute_fate_probabilities(solver="direct")
fb = g2.fate_probabilities
sampleID = adata.obs.index.tolist()
fate_name = fb.names.tolist()
fb = pd.DataFrame(fb,index= sampleID,columns=fate_name)
fate_prob2 = pd.DataFrame(columns= terminal_states, index=sampleID)

for i in terminal_states_perturb:
fate_prob2.loc[:,i] = fb.loc[:,i]

fate_prob2 = fate_prob2.fillna(0)
arr = np.array(fate_prob2.sum(0))
arr[arr!=0] = 1
fate_prob = fate_prob * arr

# Abundance test
fate_prob2.index = [i + "_perturb" for i in fate_prob2.index]
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