STELLA v1.0.0

STELLA v1.0.0 — Initial Release

Self-Evolving Multimodal Agents for Biomedical Research

Highlights

• Multi-agent framework with Manager, Dev, and Critic agents
• Self-evolving Tool Ocean for biomedical research tasks
• Dynamic knowledge base with reasoning templates and self-correction
• Web UI (Gradio) and CLI interfaces
• Memory-enhanced mode with Mem0 integration

Online Version

Try STELLA without any setup at stella-agent.com — no installation or API keys required!

Key Results

• 4.01/5 score on custom benchmark with 100% task completion
• Identified BTN3A1 as a novel regulator in acute myeloid leukemia (CRISPR-verified)
• Enzyme variants with >2x improvement in catalytic activity
• Robotic lab automation: success rates from 17% to 82%

Quick Start

# Clone and install
git clone https://github.com/zaixizhang/STELLA.git
cd STELLA
pip install -r requirements.txt

# Run
python stella_core.py --use_template --use_mem0

Links

• Paper: https://www.biorxiv.org/content/10.1101/2025.07.01.662467v2
• Online Demo: https://stella-agent.com/
• arXiv: https://arxiv.org/abs/2507.02004