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FUMA-data

This is an attempt for an automated way to download and reproduce fuma reference data.

Data repositories and tools currently used in FUMA:

Here is the table reformatted to markdown:

Source: https://static-content.springer.com/esm/art%3A10.1038%2Fs41467-017-01261-5/MediaObjects/41467_2017_1261_MOESM1_ESM.docx

Category Name Description Last accessed Link
Reference Variants dbSNP 146 Map rsID of input files to dbSNP build 146 18-Mar-16 link
Reference Genome 1000 Genomes Project Phase3 Compute MAF and r2 for each available population 25-Apr-16 link
Functional annotations of SNPs CADD v1.3 Deleteriousness score of variants 09-Jul-16 link
Functional annotations of SNPs RegulomeDB Score of regulatory variants 16-Feb-16 link
Functional annotations of SNPs 15-core chromatin state Chromatin states of genomic region in 127 tissue/cell types 15-May-16 link
Functional annotations of SNPs GWAS catalog Known trait associated variants 05-Oct-16 link
eQTLs GTEx v6 cis-eQTLs of 44 tissue types 16-Mar-16 link
eQTLs Blood eQTL Browser cis-eQTLs of blood cell 06-Jun-16 link
eQTLs BIOS QTL Browser cis-eQTLs of blood cell 07-Oct-16 link
eQTLs BRAINEAC cis-eQTLs of 10 brain regions 09-Sep-16 link
HiC GSE87112 HiC data for 14 tissue types and 7 cell lines 24-Apt-17 link
Regulatory elements Roadmapc epigenomics project Enhancer, promoter and dyadic enhancer/promoter regions in 111 epigenomes 24-Apt-17 link
Gene score pLI Probability of being loss-of-function intolerance 24-Apt-17 link
Gene score ncRVIS Non-coding residual variation intolerance score 24-Apt-17 link
Gene expression GTEx v6 Normalized gene expression (RPKM: Read Per Kilo base per Million) for 53 tissue types 16-Mar-16 link
Gene sets MsigDB v5.2 Curated pathways and gene sets 26-Dec-16 link
Gene sets WikiPathways Curated pathways 22-Apr-16 link
Tools ANNOVAR Variant annotation tool 11-Feb-16 link
Tools MAGMA v6.0 Software for gene-based test and gene-set analyses of GWAS 17-Jan-17 link

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This is an attempt for an automated way to download and reproduce fuma reference data.

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