Reproductive and developmental toxicity are the focus of this project, which employs a Neo4j graph database (knowledge graph) and heterogeneous datasets from several NIH Common Fund projects: LINCS, Kids First, SPARC, and IDG.
- "Toxicology knowledge graph for structural birth defects", John Erol Evangelista, Daniel J. B. Clarke, Zhuorui Xie, Giacomo B. Marino, Vivian Utti, Sherry L. Jenkins, Taha Mohseni Ahooyi, Cristian G. Bologa, Jeremy J. Yang, Jessica L. Binder, Praveen Kumar, Christophe G. Lambert, Jeffrey S. Grethe, Eric Wenger, Deanne Taylor, Tudor I. Oprea, Bernard de Bono & Avi Ma’ayan; Nature Communications Medicine volume 3, Article number: 98 (2023).
This repository initiated and copied from: https://github.com/druggablegenome/idg-cfde/tree/main/ReproTox