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Exfiles (expression-profiles)

Gene expression profiles and analytics. Developed by UNM for the NIH Data Commons Pilot Phase Consortium as part of Key Capability 8, Scientific Use Cases. GTEx RNAseq pre-processing and analysis workflows initially developed by Oleg Ursu and Giovanni Bocci. Jupyter notebooks and Python/Pandas port by Jeremy Yang. Dockerization and Cloud/AWS tooling by Mike Garcia. See R Shiny app at https://unmtid-shinyapps.net/exfiles/.

Dependencies

  • Python 3.6+; Pandas, BioClients
  • R 3.6+; readr, data.table, labdsv, wCorr

Workflow

See WORKFLOW.md

Glossary

Term Description
TPM Transcripts per million
Log2FoldChange LOG2(TPM_F/TPM_M)
Tau Tissue specificity index (Yanai et al., 2004)

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Gene expression profiles analytics.

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