Rgfatools is an R/Bioconductor package that provides an interface to the gfatools utilities for manipulating GFA (Graph Fragment Alignment) and rGFA (reference GFA) formats. More detailed documentation for each format can be had from Heng Li's github and the resources linked therein.

This package is designed to bring pangenome/genome graph support to Bioconductor by providing tools and utilities for manipulating genome graph representations. It is not a drop-in solution for graph alignment or variant annotation tasks!

At present, it's also unstable. I'm wrapping gfatools in the style of Rsamtools.