This repository contains models and simulations for studying the effects of cytotoxic T lymphocytes (CTLs) and chemotherapy on tumor cells for the ERC-funded project "sublethal". The project includes both deterministic and stochastic models implemented in Python.
Simulates the damage and repair of intracellular components, focusing on calcium ions and foci formation.
Simulates the interaction between tumor cells, CTLs, and chemotherapy, considering various rates of cell death, repair, and proliferation.
Implements stochastic simulations using the Gillespie algorithm to model CTL-mediated tumor cell damage and the effects of chemotherapy.
For any questions or issues, please contact the repository owner.