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Regenie v3.6

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@joellembatchou joellembatchou released this 03 Sep 15:28
· 64 commits to master since this release
v3.6
b2a8683
  • Bug fix for the approximate Firth test when ultra-rare variants (MAC<50) are being tested:
    • Fix to the calculation of the null deviance used in the likelihood ratio test.
    • BETA estimates remain unchanged, but p-value will change (SE will also change if using --firth-se).
    • This fix also addresses convergence failures with Firth.
  • Improvements to address convergence failures & speed-up exact Firth by using warm starts based on null model with just covariates.
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