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Regenie v3.4

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@joellembatchou joellembatchou released this 14 Dec 22:12
· 92 commits to master since this release
v3.4
51968de
  • Reduction in memory usage for LD computation when dosages are present;
    • compute LD matrix block-wise rather than all at once
    • expected memory usage is (3NB+ M^2)*8 bytes where N is sample size, B is block size and M is number of variants in LD matrix
    • we recommend using blocks of sizes 1000 as choosing too small block size will increase the number of block pairs evaluated
  • Minor bug fixes for LD computation;
  • Bug fix for carriage return in optional files
    • in keep/remove/extract/exclude/mask-definition/annotation files
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