miR2Trait

An integrated resource for investigating miRNA - disease associations

The code and data comprising the miR2Trait resource are described in the miR2Trait wiki. All code is developed using Python 3.x

Code wikis:

1. Creating Python dictionary data structures of processed DisGeNET data
2. Creating Python dictionary data structures of processed miRTarBase data
3. Generating the miR2Trait db mappings
4. Querying miR2Trait by disease
5. Querying miR2trait by miRNA
6. miRNA List Enrichment Analysis
7. Disease Set Abundance Analysis
8. Creation of miRNA-miRNA and disease-disease adjacency networks
9. Top Nodes from Adjacency Networks -- Network post-processing to yield consensus central nodes
10. Querying miRNA information from miRBase
11. Creating a toy MySQLdb

Data wikis:

1. Processed Source data
2. miR2Trait mappings
3. Spectrum widths
4. Adjacency networks
5. Human miRNA catalog

Dependencies:

Following Python 3.x libraries are required:

• pandas
• scipy
• pickle
• mysql-connector-python (optional: for creation of MySQL db)

For more details, reproducible examples, and citation, please see:

Babu P, Palaniappan A. 2022. miR2Trait: an integrated resource for investigating miRNA-disease associations. PeerJ 10:e14146 https://doi.org/10.7717/peerj.14146

E-mail: apalania.at.scbt.sastra.edu