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CRISPR-based functional screening of cancer genes.

Analysis pipeline for study entitled, High-throughput functional evaluation of human cancer-associated mutations using base editors, https://doi.org/10.1038/s41587-022-01276-4

  • Candidate selection by surveying CCDS, gnomAD, and COSMIC databases.
  • Functional/pathogenic screening of candidates using ANNOVAR
  • Output to VCF

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CRISPR-based functional screening of cancer genes

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