Surrounding Region Dependence Method for Detection of Clustered Microcalcifications
You can read more about Surrounding region dependence method: http://ieeexplore.ieee.org/xpl/login.jsp?tp=&arnumber=635642&url=http%3A%2F%2Fieeexplore.ieee.org%2Fxpls%2Fabs_all.jsp%3Farnumber%3D635642
Surrounding Region Dependence Method for Detection of Clustered Microcalcifications http://koasas.kaist.ac.kr/bitstream/10203/9844/1/24.pdf
You can set the SRD parameters on a GUI and analyze the image, the tool is also able to figure out the best parameters settings.
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