SIEVE is an intereactive visualization for exploring breakthrough sequence data from vaccine efficacy trials. Specifically, SIEVE aids the process of "sieve analysis", which compares the genetic sequences of viruses isolated from infected vaccine versus placebo recipients. The visualization allows researchers to study the effect of the vaccine at the level of the amino acids in the breakthrough viruses and find statistically significant differences in the groups.
Access SIEVE here.
- University of Washington: N. Kullman, G. Glenaghan, W. Yang
- Fred Hutchinson Cancer Research Center: A. Fiore-Gartland, A. DeCamp
- UW eScience Institute