The tool calculates power for the Bayesian pick-the-winner design in a randomized phase II clinical trial. It also generates report and statistical plan so clinicians could easily incorporate it into the clinical trial protocol. (reference: A Bayesian pick-the-winner design in a randomized phase II clinical trial; Chen et al; submitted).
- The shiny applictaion provides power calculation for the Bayesian pick-the-winner design in a randomized phase II clinical trial and generates a statistical plan to be easily incorporated into the clinical trial protocol.
- Chen DT, Huang PY, Lin HY, Chiappori AA, Gabrilovich DI, Haura EB, Antonia SJ, Gray JE. A Bayesian pick-the-winner design in a randomized phase II clinical trial. Oncotarget. 2017 Jul 7;8(51):88376-88385. doi: 10.18632/oncotarget.19088. PMID: 29179442; PMCID: PMC5687612.
Simply run the following from an R console:
if (!require("devtools"))
install.packages("devtools")
devtools::install_github("dungtsa/BayesianPickWinner",force = TRUE)require("BayesianPickWinner")
bayes.pick.winner()Snapshot of shiny app: initial
Snapshot of shiny app: output
Snapshot of shiny app: output in Word format (through "download" button)
