Just DNA Lite v0.2.1

Installation

Windows: Download JustDNALite-0.2.1-Setup.exe, run the installer, then launch from the Start Menu or Desktop shortcut.

macOS (Apple Silicon M1-M4): Download JustDNALite-0.2.1-arm64.dmg, open it, and drag Just DNA Lite to your Applications folder.

macOS (Intel): Download JustDNALite-0.2.1-x64.dmg, open it, and drag Just DNA Lite to your Applications folder.

First launch takes 1-3 minutes (downloads Python and dependencies). Subsequent launches are fast.

macOS note: Since the app is not yet notarized, you may need to right-click the app and select "Open" on first launch to bypass Gatekeeper.

For Linux or advanced usage, see the README.

What's Changed

• Add Nix flake for Mac users by @teranos in #1
• Add Nix CI for ARM targets and fix stale tests by @teranos in #2
• Harden CI: Cachix cache, test markers, weekly integration job by @teranos in #5

New Contributors

• @teranos made their first contribution in #1

Full Changelog: v0.1.3...v0.2.1

v0.1.3 - Medical Disclaimer & Legal Safety

What's Changed

Legal & Medical Safety

• Added explicit MEDICAL DISCLAIMER to README — software is not a medical device, provided AS IS, zero liability
• Strengthened top-level RUO block with "not a medical device" and "no medical advice" language
• Added Limitation of Liability clause to the License section (AS IS, no warranties)
• Softened EHDS language to avoid asserting specific legal rights under EU regulation
• Added prominent medical disclaimer blockquote to docs/SCIENCE_LITERACY.md

Web UI

• Updated topbar RUO badge to "Medical Disclaimer / RUO" with improved tooltip
• Updated onboarding welcome banner: now reads "MEDICAL DISCLAIMER & Research Use Only (RUO)", explicitly states "not a medical device", and includes a no-liability statement

No breaking changes. No functional changes to the pipeline or annotation logic.

v0.1.2

What's New in v0.1.2

PRS Integration

• Integrated just-prs and prs-ui for Polygenic Risk Score computation via PGS Catalog
• Background PRS execution with results persistence
• LazyFrame-based genotype input for memory-efficient scoring

Module Creator System

• Module creator with updates and fixes
• Module editing and versioning support

AI & Agents

• Advanced agents with MCP integration
• Researcher team support

Pipeline & UI Improvements

• Ensembl annotation UI updates
• VCF viewer (partial)
• Port auto-select for smoother startup
• Multiple bugfixes and reliability improvements
• Report generation fixes