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Twostep

The source code for the Simulation and application in the "Integration of Proxy Intermediate Omics traits into a Nonlinear Two-Step model for accurate phenotypic prediction" was uploaded here.

doi: https://doi.org/10.1101/2025.03.14.643213

Repository structure

Functions

File Model / Purpose
MyFunctions.R Custom helper functions

Simulation

File Model / Purpose
1_bb.Rmd BLUP–BLUP
2_rr.Rmd RF–RF
3_rb.Rmd RF–BLUP
4_br.Rmd BLUP–RF
5_compare.Rmd Model comparison

Application

File Description
1_metpred.Rmd Metabolome prediction
2_phenopred_GMet.Rmd Phenotype prediction using genomic + metabolomic data
3_phenopred_GMicroMet.Rmd Phenotype prediction using genomic + micro + metabolomic data

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The source code for the Simulation and application in the "Integration of Proxy Intermediate Omics traits into a Nonlinear Two-Step model for accurate phenotypic prediction"

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