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This repository contains the code accompanying Coorens et al, 'Extensive phylogenies of human development reveal variable embryonic patterns', 2020.

Filtering of variant calls

Scripts used to filter single nucleotide variant calls from CaVEMan can be found in the Filters/ folder. In brief, these include a script for filtering of germline variants using an exact binomial test and a script to filter artefacts based on the beta-binomial overdispersion coefficient.

Scripts for analysis

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Code accompanying "Extensive phylogenies of human development inferred from somatic mutations" (Coorens et al., 2021, Nature)

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