Skip to content
Merged
Show file tree
Hide file tree
Changes from all commits
Commits
File filter

Filter by extension

Filter by extension

Conversations
Failed to load comments.
Loading
Jump to
Jump to file
Failed to load files.
Loading
Diff view
Diff view
21 changes: 21 additions & 0 deletions src/pmotools/pmo_engine/pmo_processor.py
Original file line number Diff line number Diff line change
Expand Up @@ -402,6 +402,27 @@ def count_library_samples_per_target(
drop=True
)

@staticmethod
def count_targets_per_panel(pmodata) -> pd.DataFrame:
"""
Count the targets per panel.

:param pmodata: the pmo to count from
:return: counts for each panel
"""
# how many targets in each panel
panels = []
target_count = []
for panel in pmodata["panel_info"]:
panel_targets = []
panels.append(panel["panel_name"])
for reaction in panel["reactions"]:
panel_targets.extend(reaction["panel_targets"])
target_count.append(len(set(panel_targets)))
return pd.DataFrame(
data={"panel_name": panels, "panel_target_count": target_count}
)

@staticmethod
def list_library_sample_names_per_specimen_name(
pmodata,
Expand Down
118 changes: 118 additions & 0 deletions tests/test_pmo_engine/test_pmo_processor.py
Original file line number Diff line number Diff line change
Expand Up @@ -873,6 +873,124 @@ def test_get_panel_names(self):
names = PMOProcessor.get_panel_names(pmo_data_combined)
self.assertEqual(["heomev1"], names)

def test_count_targets_per_panel_single_panel_single_reaction(self):
"""Test count_targets_per_panel with a single panel containing one reaction"""
# Create a simple PMO with one panel and one reaction
test_pmo = {
"panel_info": [
{
"panel_name": "test_panel_1",
"reactions": [
{
"reaction_name": "reaction_1",
"panel_targets": [0, 1, 2, 3, 4],
}
],
}
]
}

result = PMOProcessor.count_targets_per_panel(test_pmo)

expected_data = {"panel_name": ["test_panel_1"], "panel_target_count": [5]}
expected_df = pd.DataFrame(expected_data)

pd.testing.assert_frame_equal(result, expected_df)

def test_count_targets_per_panel_single_panel_multiple_reactions(self):
"""Test count_targets_per_panel with a single panel containing multiple reactions"""
# Create a PMO with one panel and multiple reactions
test_pmo = {
"panel_info": [
{
"panel_name": "test_panel_1",
"reactions": [
{"reaction_name": "reaction_1", "panel_targets": [0, 1, 2]},
{"reaction_name": "reaction_2", "panel_targets": [3, 4, 5, 6]},
{"reaction_name": "reaction_3", "panel_targets": [7, 8]},
],
}
]
}

result = PMOProcessor.count_targets_per_panel(test_pmo)

expected_data = {
"panel_name": ["test_panel_1"],
"panel_target_count": [9], # 3 + 4 + 2 = 9 total targets
}
expected_df = pd.DataFrame(expected_data)

pd.testing.assert_frame_equal(result, expected_df)

def test_count_targets_per_panel_multiple_panels(self):
"""Test count_targets_per_panel with multiple panels"""
# Create a PMO with multiple panels
test_pmo = {
"panel_info": [
{
"panel_name": "panel_A",
"reactions": [
{"reaction_name": "reaction_1", "panel_targets": [0, 1, 2, 3]}
],
},
{
"panel_name": "panel_B",
"reactions": [
{"reaction_name": "reaction_1", "panel_targets": [4, 5]},
{
"reaction_name": "reaction_2",
"panel_targets": [6, 7, 8, 9, 10],
},
],
},
{
"panel_name": "panel_C",
"reactions": [
{"reaction_name": "reaction_1", "panel_targets": [11]}
],
},
]
}

result = PMOProcessor.count_targets_per_panel(test_pmo)

expected_data = {
"panel_name": ["panel_A", "panel_B", "panel_C"],
"panel_target_count": [4, 7, 1], # 4, (2+5), 1
}
expected_df = pd.DataFrame(expected_data)

pd.testing.assert_frame_equal(result, expected_df)

def test_count_targets_per_panel_with_real_data_structure(self):
"""Test count_targets_per_panel with realistic PMO data structure"""
# Create a realistic PMO structure similar to the real data
# Based on the real data structure with one panel containing 100 targets
test_pmo = {
"panel_info": [
{
"panel_name": "heomev1",
"reactions": [
{
"panel_targets": list(range(100)), # targets 0-99
"reaction_name": "full",
}
],
}
]
}

result = PMOProcessor.count_targets_per_panel(test_pmo)

expected_data = {
"panel_name": ["heomev1"],
"panel_target_count": [100], # targets 0-99 = 100 total
}
expected_df = pd.DataFrame(expected_data)

pd.testing.assert_frame_equal(result, expected_df)


if __name__ == "__main__":
unittest.main()