CustomProteinSearch is a python package containing two independent but complementary programs whose overall objective is to help users to search for specific proteins of interest based on their domain composition: IterHMMBuildand ProSeCDA.
IterHMMBuild is an iterative search method based on the hmmer program, the aim of which is to provide users with a representative HMM protein profile of interest constructed by an iterative enrichment process starting from a small initial set of related protein sequences.
ProSeCDA is a tool that allows to search in a given protein database multiple proteins of interest defined by a user-specified set of domains.
Please see our documentation for details about the package and how to install it.
Note: CusProSE is actually not supported on Windows, we'll fix this later.