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BBerickson/README.md

Bioinformatics Scientist | Genomics Researcher | Pipeline Developer

I'm a wet bench and computational biologist with 19+ years of experience in transcriptional regulation research, specializing in ChIP-seq and RNA-seq analysis. I develop tools and pipelines that transform raw sequencing data into biological insights.

πŸ”¬ Currently: Senior Research Assistant at University of Colorado Anschutz, Bentley Lab
πŸ“ Location: Denver, Colorado
πŸ“§ Contact: Benjamin.Erickson@cuanschutz.edu


🧬 Research Focus

  • Transcriptional regulation and RNA Polymerase II dynamics
  • Nascent RNA sequencing (NETseq, BrUseq, ChIPseq)
  • Alternative splicing and RNA processing
  • Chromatin modifications and gene expression

πŸ› οΈ Technical Expertise

Genomics & Bioinformatics:

ChIP-seq β€’ RNA-seq β€’ NET-seq β€’ BRU-seq β€’ Differential Expression β€’ Peak Calling
Alternative Splicing β€’ RNA Editing β€’ Motif Analysis

Programming & Data Science:

R Python Bash Docker AWS

Bioinformatics Tools:

STAR β€’ Bowtie2 β€’ samtools β€’ bedtools β€’ deepTools β€’ MACS β€’ HOMER
DESeq2 β€’ rMATS β€’ MAJIQ β€’ Salmon β€’ SUPPA β€’ BBtools β€’ Snakemake

πŸ“¦ Featured Projects

🧰 BenTools

Custom R package for genomics data analysis and visualization. Functions for processing ChIP-seq and RNA-seq data with publication-quality plotting capabilities.

Key Features: Metagene plots β€’ Coverage analysis β€’ Custom genomic visualizations

Production-ready Snakemake workflows for processing sequencing data. Automated, reproducible pipelines from raw FASTQ to publication-ready results.

Technologies: Snakemake β€’ Docker β€’ Cluster computing

Interactive Shiny application for RNA-seq and ChIP-seq data exploration and visualization. Enables researchers to analyze data without programming knowledge.

Stack: R Shiny β€’ ggplot2 β€’ Interactive dashboards


πŸ“š Publications

Author on 19 peer-reviewed publications in high-impact journals including:

  • Cell Reports (First Author, 2024)
  • PNAS (2024, 2011)
  • Genes & Development (First Author, 2018, 2022)
  • Molecular Cell (2019, 2015, 2012)
  • eLife (2024, 2022, 2021)
  • Nature Structural & Molecular Biology (2011, 2010)

πŸ“– View full publication list on Google Scholar
πŸ”¬ View profile on ResearchGate


πŸŽ“ Certifications

  • R Programming (Coursera)
  • Getting and Cleaning Data (Coursera)
  • Reproducible Research (Coursera)
  • Interactive Programming in Python (Coursera)

πŸ“« Connect With Me

Email LinkedIn


πŸ“Š GitHub Stats

Ben's GitHub stats


"Transforming sequencing data into biological discoveries through computational innovation"

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