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AminaHanan246/README.md

👋 Hi, I’m Hanaan

🧬 I’m passionate about leveraging computational tools (Python, R) to solve biological problems, especially in genomics and transcriptomics.
🔬 I’m currently sharpening my skills in RNA-seq analysis and building robust data pipelines.
🤝 I’m looking to collaborate on open-source bioinformatics projects or genomics research.

📫 Reach me at: aminahanaan0310@gmail.com

       email

✅ Completed projects:

Tech Stacks: Nextflow BWA-MEM GATK fastp picard bcftools Conda

Developed scalable pipeline for Whole Exome Sequence analysis, that automates workflow from raw reads to filtered-variants and ability to handle multiple cohort samples. Built using Mextflow and following GATK best practises documentation.

Tech Stacks: Python Scikit-learn Logistic-Regression Random-Forest XGBoost Cross-validation Hyperparameter-tuning SHAP PCA Top features

Developed and documented a machine learning workflow from raw gene expression data to identifying potential biomarkers in Alzheimer's Disease. The dataset contains 206 samples and 19,297 genes classified into control and condition classes.

Tech Stacks: Bash scripting Python R FASTQC Trimmomatic HISAT2 SAMtools featureCounts DESeq2 GSEA

Implemented and documented a complete bulk RNA-seq workflow from raw SRA data to differential expression and pathway enrichment analysis for 8 samples under 4 conditions (~78,894 genes)

⏳ Ongoing:

Tech Stacks: R Seurat

🧬 Fundamentals & Case studies:

Tech Stacks: Python Scikit-learn Logistic-Regression Decision-Tree Random-Forest Hyperparameter-tuning

A series of tasks that are core to bioinformatic skills.

💻 Tech Stack:

Python R Bash Script Matplotlib Pandas scikit-learn NumPy Git GitHub Notion Canva Gimp

📊 GitHub Stats:




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  1. bulk_rna_seq_prj bulk_rna_seq_prj Public

    Bulk-RNA seq workflow

    R 1

  2. ML_alzheimer_gene_ ML_alzheimer_gene_ Public

    Gene-based classification of Alzheimer's Disease using ML models

    Python 2

  3. scRNA scRNA Public

    scRNA

    R

  4. variant_call_hcm variant_call_hcm Public

    Variant calling on WES data on Hypertrophic cardiomyopathy (HCM) patients (human)

    HTML