diff --git a/setup.py b/setup.py
index 8c1ceaf..a7ed778 100644
--- a/setup.py
+++ b/setup.py
@@ -24,7 +24,7 @@
 
         install_requires=[
             'six==1.12.0',
-            'numpy==1.16.4',
+            'numpy==1.22.0',
             'weave==0.17',
             'scipy==1.2.1',
             'biopython==1.73',