diff --git a/mutect/filter_mutect.py b/mutect/filter_mutect.py index aba06fb..d7856dd 100644 --- a/mutect/filter_mutect.py +++ b/mutect/filter_mutect.py @@ -44,7 +44,7 @@ def main(): parser.add_argument("-tsn", "--tsampleName", action="store", dest="tsampleName", required=True, type=str,metavar='SomeName', help="Name of the tumor Sample") parser.add_argument("-dp", "--totaldepth", action="store", dest="dp", required=False, type=int, default=0, metavar='0', help="Tumor total depth threshold") parser.add_argument("-ad", "--alleledepth", action="store", dest="ad", required=False, type=int, default=5, metavar='5', help="Tumor allele depth threshold") - parser.add_argument("-tnr", "--tnRatio", action="store", dest="tnr", required=False, type=int, default=5, metavar='5', help="Tumor-Normal variant frequency ratio threshold ") + parser.add_argument("-tnr", "--tnRatio", action="store", dest="tnr", required=False, type=int, default=0, metavar='0', help="Tumor-Normal variant frequency ratio threshold ") parser.add_argument("-vf", "--variantfrequency", action="store", dest="vf", required=False, type=float, default=0.01, metavar='0.01', help="Tumor variant frequency threshold ") parser.add_argument("-hvcf", "--hotspotVcf", action="store", dest="hotspotVcf", required=False, type=str, metavar='hostpot.vcf', help="Input bgzip / tabix indexed hotspot vcf file to used for filtering") parser.add_argument("-o", "--outDir", action="store", dest="outdir", required=False, type=str, metavar='/somepath/output', help="Full Path to the output dir.") diff --git a/pindel/filter_pindel.py b/pindel/filter_pindel.py index 381d546..8a58689 100644 --- a/pindel/filter_pindel.py +++ b/pindel/filter_pindel.py @@ -87,8 +87,8 @@ def main(): dest="tnr", required=False, type=int, - default=5, - metavar='5', + default=0, + metavar='0', help="Tumor-Normal variant frequency ratio threshold ") parser.add_argument( "-vf", diff --git a/somaticindeldetector/filter_sid.py b/somaticindeldetector/filter_sid.py index a7a6e0e..1c40392 100644 --- a/somaticindeldetector/filter_sid.py +++ b/somaticindeldetector/filter_sid.py @@ -95,8 +95,8 @@ def main(): dest="tnr", required=False, type=int, - default=5, - metavar='5', + default=0, + metavar='0', help="Tumor-Normal variant frequency ratio threshold ") parser.add_argument( "-vf", @@ -245,4 +245,4 @@ def checkHotspot(hotspotVcf, chromosome, start): end_time = time.time() totaltime = end_time - start_time logging.info("filter_sid: Elapsed time was %g seconds", totaltime) - sys.exit(0) \ No newline at end of file + sys.exit(0) diff --git a/vardict/filter_vardict.py b/vardict/filter_vardict.py index b35e816..ec3540d 100644 --- a/vardict/filter_vardict.py +++ b/vardict/filter_vardict.py @@ -86,8 +86,8 @@ def main(): dest="tnr", required=False, type=int, - default=5, - metavar='5', + default=0, + metavar='0', help="Tumor-Normal variant frequency ratio threshold ") parser.add_argument( "-vf",