diff --git a/rules-tests/CodeQuality/Rector/ClassMethod/NoSetupWithParentCallOverrideRector/Fixture/skip_indirect_parent_testcase.php.inc b/rules-tests/CodeQuality/Rector/ClassMethod/NoSetupWithParentCallOverrideRector/Fixture/skip_indirect_parent_testcase.php.inc
new file mode 100644
index 00000000..beb72f3b
--- /dev/null
+++ b/rules-tests/CodeQuality/Rector/ClassMethod/NoSetupWithParentCallOverrideRector/Fixture/skip_indirect_parent_testcase.php.inc
@@ -0,0 +1,16 @@
+<?php
+
+namespace Rector\PHPUnit\Tests\CodeQuality\Rector\ClassMethod\NoSetupWithParentCallOverrideRector\Fixture;
+
+use Rector\PHPUnit\Tests\CodeQuality\Rector\ClassMethod\NoSetupWithParentCallOverrideRector\Source\SomeFunctionalTestCase;
+
+final class SkipIndirectParentTestCase extends SomeFunctionalTestCase
+{
+    #[\Override]
+    protected function setUp(): void
+    {
+        parent::setUp();
+
+        $some = 'value';
+    }
+}
diff --git a/rules-tests/CodeQuality/Rector/ClassMethod/NoSetupWithParentCallOverrideRector/Source/SomeFunctionalTestCase.php b/rules-tests/CodeQuality/Rector/ClassMethod/NoSetupWithParentCallOverrideRector/Source/SomeFunctionalTestCase.php
new file mode 100644
index 00000000..d46fcb5f
--- /dev/null
+++ b/rules-tests/CodeQuality/Rector/ClassMethod/NoSetupWithParentCallOverrideRector/Source/SomeFunctionalTestCase.php
@@ -0,0 +1,13 @@
+<?php
+
+namespace Rector\PHPUnit\Tests\CodeQuality\Rector\ClassMethod\NoSetupWithParentCallOverrideRector\Source;
+
+abstract Class SomeFunctionalTestCase extends \PHPUnit\Framework\TestCase
+{
+    protected function setUp(): void
+    {
+        parent::setUp();
+
+        init_db();
+    }
+}
diff --git a/rules/CodeQuality/Rector/ClassMethod/NoSetupWithParentCallOverrideRector.php b/rules/CodeQuality/Rector/ClassMethod/NoSetupWithParentCallOverrideRector.php
index cfc0e27b..a778d0c3 100644
--- a/rules/CodeQuality/Rector/ClassMethod/NoSetupWithParentCallOverrideRector.php
+++ b/rules/CodeQuality/Rector/ClassMethod/NoSetupWithParentCallOverrideRector.php
@@ -78,7 +78,7 @@ public function getNodeTypes(): array
      */
     public function refactor(Node $node): ?Node
     {
-        if (! $this->testsNodeAnalyzer->isInTestClass($node)) {
+        if (! $this->testsNodeAnalyzer->isDirectlyExtendsTestCase($node)) {
             return null;
         }
 
diff --git a/src/NodeAnalyzer/TestsNodeAnalyzer.php b/src/NodeAnalyzer/TestsNodeAnalyzer.php
index d2b90e5a..4c162443 100644
--- a/src/NodeAnalyzer/TestsNodeAnalyzer.php
+++ b/src/NodeAnalyzer/TestsNodeAnalyzer.php
@@ -43,6 +43,21 @@ public function isInTestClass(Node $node): bool
         return false;
     }
 
+    public function isDirectlyExtendsTestCase(ClassMethod $classMethod): bool
+    {
+        $classReflection = $this->reflectionResolver->resolveClassReflection($classMethod);
+        if (! $classReflection instanceof ClassReflection) {
+            return false;
+        }
+
+        $parents = $classReflection->getParents();
+        if ($parents === []) {
+            return false;
+        }
+
+        return in_array($parents[0]->getName(), PHPUnitClassName::TEST_CLASSES, true);
+    }
+
     public function isTestClassMethod(ClassMethod $classMethod): bool
     {
         if (! $classMethod->isPublic()) {