Implementing Patlak model #50
Description
Hi there,
Our team would be interested in using Quantiphyse for our new project involving T1-DCE. Our clinical collaborators recommended we use the Patlak model [1,2] instead of those already available in Quantiphyse.
We were wondering if it would be feasible to have the Patlak model available in Quantiphyse. Thank you.
References:
[1] Patlak CS, Blasberg RG, Fenstermacher JD. Graphical Evaluation of Blood-to-Brain Transfer Constants from Multiple-Time Uptake Data. Journal of Cerebral Blood Flow & Metabolism. 1983;3(1):1-7. doi:10.1038/jcbfm.1983.1
[2] Larsson HB, Courivaud F, Rostrup E, Hansen AE. Measurement of brain perfusion, blood volume, and blood-brain barrier permeability, using dynamic contrast-enhanced T(1)-weighted MRI at 3 tesla. Magn Reson Med. 2009 Nov;62(5):1270-81. doi: 10.1002/mrm.22136. PMID: 19780145.