steps.txt

sudo apt-get update
sudo apt-get install pdns-server pdns-backend-mysql mysql-server libmysqlclient-dev python-pip python-virtualenv python-dev  
sudo pip install virtualenvwrapper

Don't forget to delete the simplebind backend for PowerDNS! MySQL is much better.

export WORKON_HOME=$HOME/Envs
export PIP_REQUIRE_VIRTUALENV=true
export PIP_RESPECT_VIRTUALENV=true
export PIP_VIRTUALENV_BASE=$WORKON_HOME
source /usr/local/bin/virtualenvwrapper.sh

mkvirtualenv reportspam
workon reportspam
mkdir -p /srv/www
# Put reportspam.py and requirements.txt in there
pip install -r requirements.txt
python reportspam.py

# Meanwhile, back on your mail server...
# Test DNS...
dig @my.dnsbl.com soa bl.mydomain.com
# Test spam reporting...
curl http://my.dnsbl.com/report/111.222.123.123

# Better, more sustainable...
apt-get install uwsgi-plugin-python uwsgi nginx

#