Welcome to ClawBio — Roadmap & How to Contribute

[manuelcorpas]

Welcome!

ClawBio is the first bioinformatics-native AI agent skill library. We launched at the London Bioinformatics Meetup on 26 February 2026 and are now building in the open.

What we have today (5 MVP skills)

Skill	Status	Tests
PharmGx Reporter	Production	24 tests
Equity Scorer	Production	24 tests
NutriGx Advisor	Production (community)	9 tests
Bio Orchestrator	Production	—
Metagenomics Profiler	Production	—

Roadmap (8 skills seeking contributors)

Check the open issues — each planned skill has a dedicated issue with full specs:

• VCF Annotator (Implement VCF Annotator skill (Python) #6) — VEP + ClinVar + gnomAD
• Lit Synthesizer (Implement Lit Synthesizer skill (Python) #7) — PubMed/bioRxiv search + synthesis
• scRNA Orchestrator (Implement scRNA Orchestrator skill (Python) #8) — Scanpy/Seurat automation
• Struct Predictor (Implement Struct Predictor skill (Python) #9) — AlphaFold/Boltz wrapper
• Seq Wrangler (Implement Seq Wrangler skill (Python) #10) — FastQC + alignment + BAM
• Repro Enforcer (Implement Repro Enforcer skill (Python) #11) — Conda/Singularity/Nextflow export
• Ancestry PCA (Implement Ancestry PCA skill (Python) #12) — SGDP reference panel PCA
• Semantic Similarity (Implement Semantic Similarity Index skill (Python) #13) — PubMedBERT disease metrics

How to contribute

1. Pick an issue tagged help wanted
2. Read the SKILL.md in that skill's directory (full specification)
3. Look at skills/nutrigx_advisor/ as a reference implementation (clean modular structure + tests)
4. Read CONTRIBUTING.md
5. Open a PR!

Questions?

Use the Q&A category for technical questions, Ideas for feature proposals, and Show and tell to share what you've built with ClawBio.

Looking forward to building this together.