[NTR] sublingual gland demilune acinar cell #3529
Description
Please check that the term does not already exist by using the ontology search tool OLS:
https://www.ebi.ac.uk/ols4/ontologies/cl
Preferred term label
sublingual gland demilune acinar cell
Synonyms (add reference(s), please)
Definition (free text, with reference(s), please. PubMed ID format is PMID:XXXXXX)
A serous exocrine acinar cell of the major salivary glands that forms crescent‑shaped caps (demilunes) on predominantly mucous acini in the sublingual gland, draining into the same acinar lumen via intercellular canaliculi and short ductules. This cell contains electron‑dense proteinaceous secretory granules, abundant rough endoplasmic reticulum, and well‑developed Golgi, and secretes a watery, glycoprotein‑rich fluid that supplements mucous saliva with digestive and antimicrobial proteins such as lysozyme and lactoferrin, contributing to oral microbial homeostasis. In humans, serous elements in this gland are largely restricted to such demilunes, in contrast to the purely serous parotid acini. Gamma‑glutamyl transpeptidase enriches serous demilunes in human salivary glands, while Dcpp1 marks homologous demilune cells in mice.
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Parent cell type term (check the hierarchy here https://www.ebi.ac.uk/ols4/ontologies/cl)
serous acinar cell of salivary gland
Anatomical structure where the cell type is found (check Uberon for anatomical structures: https://www.ebi.ac.uk/ols4/ontologies/uberon)
sublingual gland
Your ORCID
Additional notes or concerns
Source for draft deepsearch https://www.perplexity.ai/search/system-role-you-are-an-expert-mgVrXEyqSRqP6OYtYuaVbQ#0