diff --git a/requirements.txt b/requirements.txt
index 4836630..473d8e5 100644
--- a/requirements.txt
+++ b/requirements.txt
@@ -8,22 +8,22 @@ contextlib2==0.6.0.post1  # via pytest-shutil
 coverage==5.0.3
 cycler==0.10.0            # via matplotlib
 execnet==1.7.1            # via pytest-shutil
-importlib-metadata==1.4.0 # via pytest
+importlib-metadata==1.5.0 # via pytest
 kiwisolver==1.1.0         # via matplotlib
-matplotlib==3.1.2
-mock==3.0.5               # via pytest-shutil
-more-itertools==8.1.0     # via pytest
+matplotlib==3.1.3
+mock==4.0.1               # via pytest-shutil
+more-itertools==8.2.0     # via pytest
 numpy==1.18.1
 packaging==20.1           # via pytest
-pandas==0.25.3
+pandas==1.0.1
 pluggy==0.13.1            # via pytest
 py==1.8.1                 # via pytest
-path.py==12.0.2           # via pytest-shutil
+path.py==12.4.0           # via pytest-shutil
 pyfaidx==0.5.8
 pyfastaq==3.17.0          # via shell scripts
 pyparsing==2.4.6          # via matplotlib, pytest
 python-dateutil==2.8.1    # via matplotlib, pandas
-pytest==5.3.4
+pytest==5.3.5
 pytest-shutil==1.7.0
 pytz==2019.3              # via pandas
 pyyaml==5.3
@@ -32,4 +32,4 @@ seaborn==0.10.0
 six==1.14.0               # via pyfaidx, python-dateutil, pytest
 termcolor==1.1.0          # via pytest-shutil
 wcwidth==0.1.8            # via pytest
-zipp==2.1.0               # via pytest
\ No newline at end of file
+zipp==2.2.0               # via pytest
\ No newline at end of file
diff --git a/setup.cfg b/setup.cfg
index f4dd687..e1a99b0 100644
--- a/setup.cfg
+++ b/setup.cfg
@@ -45,21 +45,21 @@ zip_safe = False
 include_package_data = True
 packages = aakbar
 install_requires =
-    biopython
+    biopython==1.76
     click>=5.0
-    click_plugins
-    colorama
-    coverage
-    matplotlib
-    numpy
-    pandas
-    path.py<=12.0.2
-    pyfaidx
-    pyfastaq
-    pytest
-    pytest-shutil
-    pyyaml
-    seaborn
+    click_plugins==1.1.1
+    colorama==0.4.3
+    coverage==5.0.3
+    matplotlib==3.1.3
+    numpy==1.18.1
+    pandas==1.0.1
+    path.py==12.4.0
+    pyfaidx==0.5.8
+    pyfastaq==3.17.0
+    pytest==5.3.5
+    pytest-shutil==1.7.0
+    pyyaml==5.3
+    seaborn==0.10.0
 
 [options.package_data]
 * =