The mouse is slow/unusable when running the CyberCIEGE lab on VirtualBox installed on OSX Catalina.
Reducing the scaling factor to 1 at least lets you move the mouse, but it is jerky and of course the game window is a postage stamp. The problem does not occur on VMWare on the same platform. And it does not occur with VirtualBox on other types of host computers.
If you have the choice, use VMWare over VirtualBox when on a Mac. VirtualBox has mouse integration problems when on a Mac.