diff --git a/requirements.txt b/requirements.txt
index 3019393..b6301e3 100644
--- a/requirements.txt
+++ b/requirements.txt
@@ -5,6 +5,6 @@ idna==2.10
 mysql-connector-python==8.0.22
 protobuf==3.13.0
 requests==2.24.0
-six==1.15.0
+six==1.16.0
 urllib3==1.25.11
 PubChemPy==1.0.4