diff --git a/extensions/cornerstone-dicom-seg/src/commandsModule.ts b/extensions/cornerstone-dicom-seg/src/commandsModule.ts
index 6845716f0b5..c73abc7b8a3 100644
--- a/extensions/cornerstone-dicom-seg/src/commandsModule.ts
+++ b/extensions/cornerstone-dicom-seg/src/commandsModule.ts
@@ -225,6 +225,7 @@ const commandsModule = ({
       // If DisplaySet of the segmentation exists, then over write it.
       const displaySet = displaySetService.getDisplaySetByUID(segmentationId);
       const defaultDataSource = dataSource ?? extensionManager.getActiveDataSource()[0];
+      const shouldOverWrite = !!displaySet?.StudyInstanceUID && !!displaySet.SeriesInstanceUID;
 
       let reportName: string,
         selectedDataSource: string,
@@ -263,11 +264,11 @@ const commandsModule = ({
               SeriesNumber: series ? undefined : 1 + priorSeriesNumber,
               predecessorImageId: series,
               // Use Series and SOP instancesUIDs if displaySet of the segmentation already exists.
-              ...(displaySet && {
+              ...(shouldOverWrite && {
                 SeriesInstanceUID: displaySet.SeriesInstanceUID,
-                SOPInstanceUID: displaySet.instances[0].SOPInstanceUID,
+                SOPInstanceUID: displaySet.instances?.[0].SOPInstanceUID,
                 SeriesNumber: displaySet.SeriesNumber,
-                Manufacturer: displaySet.instances[0].Manufacturer,
+                Manufacturer: displaySet.instances?.[0].Manufacturer,
               }),
             },
           };
diff --git a/extensions/default/src/Actions/createReportAsync.tsx b/extensions/default/src/Actions/createReportAsync.tsx
index 502e72ae135..46e442768ca 100644
--- a/extensions/default/src/Actions/createReportAsync.tsx
+++ b/extensions/default/src/Actions/createReportAsync.tsx
@@ -25,7 +25,8 @@ async function createReportAsync({
       .getDisplaySetsForSeries(SeriesInstanceUID)
       ?.find(ds => ds.instances.some(instance => instance.SOPInstanceUID === SOPInstanceUID));
 
-    const shouldOverWrite = displaySet && displaySet.Modality === 'SEG';
+    const shouldOverWrite =
+      displaySet?.StudyInstanceUID && displaySet.SeriesInstanceUID && displaySet.Modality === 'SEG';
 
     if (!naturalizedReport) {
       return;
diff --git a/extensions/default/src/commandsModule.ts b/extensions/default/src/commandsModule.ts
index dcbbd4fbe8a..b400f9cf824 100644
--- a/extensions/default/src/commandsModule.ts
+++ b/extensions/default/src/commandsModule.ts
@@ -654,10 +654,10 @@ const commandsModule = ({
       const deidSeriesUIDs = params.getAll('SeriesInstanceUIDs');
 
       const studyDisplaySets = displaySetService.getDisplaySetsBy(ds =>
-        deidStudyUIDs.includes(ds.instance.DeidStudyInstanceUID)
+        deidStudyUIDs.includes(ds.instance?.DeidStudyInstanceUID)
       );
       const displaySets = studyDisplaySets.filter(
-        ds => !deidSeriesUIDs.length || deidSeriesUIDs.includes(ds.instance.DeidSeriesInstanceUID)
+        ds => !deidSeriesUIDs.length || deidSeriesUIDs.includes(ds.instance?.DeidSeriesInstanceUID)
       );
 
       // If the series filtered displaysets are empty, then use study filtered displaysets.