diff --git a/cypress/support/api/profile-pictures.js b/cypress/support/api/profile-pictures.js
index 1811dd9866..bc69cb99ff 100644
--- a/cypress/support/api/profile-pictures.js
+++ b/cypress/support/api/profile-pictures.js
@@ -18,3 +18,25 @@ Cypress.Commands.add('updateProfilePictureSetting', (entryId, updatedBody) => {
     return body;
   });
 });
+
+Cypress.Commands.add('createProfilePictureSetting', () => {
+  const requestBody = {
+    scope: 'mod-users',
+    key: 'PROFILE_PICTURE_CONFIG',
+    value: {
+      enabled: true,
+      maxFileSize: 5.0,
+      encryptionKey: 'ThisIsASimpleDefaultKeyToTestIts',
+      enabledObjectStorage: false,
+    },
+  };
+
+  cy.okapiRequest({
+    method: 'POST',
+    path: 'users/settings/entries',
+    body: requestBody,
+    isDefaultSearchParamsRequired: false,
+  }).then(({ body }) => {
+    return body;
+  });
+});
diff --git a/cypress/support/fragments/users/profilePicture.js b/cypress/support/fragments/users/profilePicture.js
index 4c73136711..9d76d2f3bb 100644
--- a/cypress/support/fragments/users/profilePicture.js
+++ b/cypress/support/fragments/users/profilePicture.js
@@ -5,9 +5,13 @@ export function enableProfilePictures() {
   cy.getProfilePictureSetting().then((respBody) => {
     const profilePictureConfig = respBody.settings[0];
 
-    if (!profilePictureConfig.value.enabled) {
-      profilePictureConfig.value.enabled = true;
-      cy.updateProfilePictureSetting(profilePictureConfig.id, profilePictureConfig);
+    if (profilePictureConfig) {
+      if (!profilePictureConfig.value.enabled) {
+        profilePictureConfig.value.enabled = true;
+        cy.updateProfilePictureSetting(profilePictureConfig.id, profilePictureConfig);
+      }
+    } else {
+      cy.createProfilePictureSetting();
     }
   });
 }