diff --git a/easybuild/toolchains/compiler/rocm_compilers.py b/easybuild/toolchains/compiler/rocm_compilers.py
new file mode 100644
index 0000000000..a3fff72984
--- /dev/null
+++ b/easybuild/toolchains/compiler/rocm_compilers.py
@@ -0,0 +1,52 @@
+##
+# Copyright 2013-2025 Ghent University
+#
+# This file is triple-licensed under GPLv2 (see below), MIT, and
+# BSD three-clause licenses.
+#
+# This file is part of EasyBuild,
+# originally created by the HPC team of Ghent University (http://ugent.be/hpc/en),
+# with support of Ghent University (http://ugent.be/hpc),
+# the Flemish Supercomputer Centre (VSC) (https://www.vscentrum.be),
+# Flemish Research Foundation (FWO) (http://www.fwo.be/en)
+# and the Department of Economy, Science and Innovation (EWI) (http://www.ewi-vlaanderen.be/en).
+#
+# https://github.com/easybuilders/easybuild
+#
+# EasyBuild is free software: you can redistribute it and/or modify
+# it under the terms of the GNU General Public License as published by
+# the Free Software Foundation v2.
+#
+# EasyBuild is distributed in the hope that it will be useful,
+# but WITHOUT ANY WARRANTY; without even the implied warranty of
+# MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE.  See the
+# GNU General Public License for more details.
+#
+# You should have received a copy of the GNU General Public License
+# along with EasyBuild.  If not, see <http://www.gnu.org/licenses/>.
+##
+"""
+EasyBuild support for Clang + Flang compiler toolchain.
+
+Authors:
+
+* Jan Reuter (jan@zyten.de)
+"""
+
+from easybuild.tools.toolchain.toolchain import SYSTEM_TOOLCHAIN_NAME
+from easybuild.toolchains.compiler.llvm_compilers import LLVMCompilers
+
+TC_CONSTANT_ROCM = "ROCm"
+
+
+class ROCmCompilers(LLVMCompilers):
+    """Compiler toolchain with ROCm compilers (amdclang/amdflang)."""
+    COMPILER_FAMILY = TC_CONSTANT_ROCM
+    SUBTOOLCHAIN = SYSTEM_TOOLCHAIN_NAME
+
+    COMPILER_CC = 'amdclang'
+    COMPILER_CXX = 'amdclang++'
+
+    COMPILER_F77 = 'amdflang'
+    COMPILER_F90 = 'amdflang'
+    COMPILER_FC = 'amdflang'
diff --git a/easybuild/toolchains/rocm_compilers.py b/easybuild/toolchains/rocm_compilers.py
new file mode 100644
index 0000000000..ffaa6146e2
--- /dev/null
+++ b/easybuild/toolchains/rocm_compilers.py
@@ -0,0 +1,45 @@
+##
+# Copyright 2013-2025 Ghent University
+#
+# This file is triple-licensed under GPLv2 (see below), MIT, and
+# BSD three-clause licenses.
+#
+# This file is part of EasyBuild,
+# originally created by the HPC team of Ghent University (http://ugent.be/hpc/en),
+# with support of Ghent University (http://ugent.be/hpc),
+# the Flemish Supercomputer Centre (VSC) (https://www.vscentrum.be),
+# Flemish Research Foundation (FWO) (http://www.fwo.be/en)
+# and the Department of Economy, Science and Innovation (EWI) (http://www.ewi-vlaanderen.be/en).
+#
+# https://github.com/easybuilders/easybuild
+#
+# EasyBuild is free software: you can redistribute it and/or modify
+# it under the terms of the GNU General Public License as published by
+# the Free Software Foundation v2.
+#
+# EasyBuild is distributed in the hope that it will be useful,
+# but WITHOUT ANY WARRANTY; without even the implied warranty of
+# MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE.  See the
+# GNU General Public License for more details.
+#
+# You should have received a copy of the GNU General Public License
+# along with EasyBuild.  If not, see <http://www.gnu.org/licenses/>.
+##
+"""
+EasyBuild support for Clang + Flang compiler toolchain.
+
+Authors:
+
+* Jan Reuter (jan@zyten.de)
+"""
+
+from easybuild.toolchains.gcccore import GCCcore
+from easybuild.toolchains.compiler.rocm_compilers import ROCmCompilers
+from easybuild.tools.toolchain.toolchain import SYSTEM_TOOLCHAIN_NAME
+
+
+class ROCmCompilersToolchain(ROCmCompilers):
+    """Compiler toolchain with AMDClang and AMDFlang compilers."""
+    NAME = 'rocm-compilers'  # Follows naming scheme used for intel-compilers & nvidia-compilers
+    COMPILER_MODULE_NAME = [NAME]
+    SUBTOOLCHAIN = [GCCcore.NAME, SYSTEM_TOOLCHAIN_NAME]