diff --git a/.github/workflows/sanitizer-check.yaml b/.github/workflows/sanitizer-check.yaml
new file mode 100644
index 0000000..5be075a
--- /dev/null
+++ b/.github/workflows/sanitizer-check.yaml
@@ -0,0 +1,21 @@
+on:
+  push:
+    branches: [main, master]
+  pull_request:
+    branches: [main, master]
+
+name: Sanitizer-check
+
+jobs:
+  Sanitizer-check:
+    runs-on: ubuntu-latest
+    container: wch1/r-debug
+
+    steps:
+      - uses: actions/checkout@v4
+
+      - name: Run sanitizer checks
+        run: |
+          Rscript -e 'install.packages("devtools", repos="http://cran.us.r-project.org")'
+          Rscript -e 'devtools::install_deps(dependencies = TRUE)'
+          Rscript scripts/run-sanitizer-checks.R
diff --git a/Makefile b/Makefile
index fee0eed..a43694b 100644
--- a/Makefile
+++ b/Makefile
@@ -40,6 +40,10 @@ setup: # install tools necessary for building the package
 document: # generate R docs from source code
 	Rscript -e "devtools::document()"
 
+.PHONY: sanitizer-check
+sanitizer-check: # run sanitizer checks using a docker image
+	docker run -it --rm -v $(pwd):/mypkg -w /mypkg wch/r-debug R -f scripts/run-sanitizer-checks.R
+
 .PHONY: help
 help: # Show help for each of the Makefile recipes.
 	@grep -E '^[a-zA-Z0-9 -]+:.*#'  Makefile | sort | while read -r l; do printf "\033[1;32m$$(echo $$l | cut -f 1 -d':')\033[00m:$$(echo $$l | cut -f 2- -d'#')\n"; done
diff --git a/scripts/run-sanitizer-checks.R b/scripts/run-sanitizer-checks.R
new file mode 100644
index 0000000..eda02a4
--- /dev/null
+++ b/scripts/run-sanitizer-checks.R
@@ -0,0 +1,5 @@
+# Check for UBSan and ASan issues
+# To run locally:
+# docker run -it --rm -v $(pwd):/mypkg -w /mypkg wch/r-debug
+# R -f scripts/run-sanitizer-checks.R
+devtools::check(args = c("--as-cran"), env = c("ASAN_OPTIONS=detect_leaks=0", "_R_CHECK_AS_CRAN_" = "true"))