forked from benjaminrich/vpcstats
-
Notifications
You must be signed in to change notification settings - Fork 7
Open
Description
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3085712/pdf/12248_2011_Article_9255.pdf
the original paper had the following equations for pred correction on original scale ( not log)
pcYij = lbij +(yij-lbij) *(med(PREDbin) - lbij)/(PREDij-lbij)
when lb = 0
reduces to
pcYij =(yij) *(med(PREDbin) )/(PREDij)
similar to how we allow LLOQ at the observation level we should allow lower bound at observation level
https://github.com/certara/tidyvpc/blob/master/R/vpcstats.R#L729
o$obs[, ypc := (mpred/pred)*y]
on a separate note we might also want to add variance correction
Reactions are currently unavailable
Metadata
Metadata
Assignees
Labels
No labels