The mouse randomly gets unresponsive during the screen log-in and connecting it into a different USB port, does not solve the problem. The only way to "fix" this issue is to do a reboot.
This issue also happened today on my brand new XPS 13 9360. The mouse became unresponsive as soon as I installed the ckb-next drivers and did a reboot. This is not an isolate case because I have the same issue on my PC Desktop I7-2600K.
Both machines are running Debian Stretch (Stable branch) 64 Bit with MATE GUI.