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Trouble Detecting Visually Apparent Cells with CNMFe #145

@omis-io

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@omis-io

Hi Biafra & Co,
I am currently using CNMFe to extract calcium signals from my Miniscope recordings. However, I have encountered an issue: despite adjusting several parameters, the extracted cells differ significantly from what I can clearly identify by eye. In particular, some cells that are visually apparent are not being extracted by the algorithm.

This issue seems to persist across multiple samples. I was wondering if you could kindly advise on which specific parameters or preprocessing steps I could try modifying to improve the detection accuracy. Are there any commonly recommended adjustments for cases like this?

Thank you very much for your time and for developing such a powerful tool. I would greatly appreciate any suggestions you might have.

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