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I don't know if you're familiar with TileDB-SOMA. I recently learned about that, and I think it might be helpful!
There's no need for the usual h5ad-to-Seurat conversion; the data lives in one Tile-Soma object on your local disk or cloud, so you can write in Python and read in R or vice versa without any conversion.
The package is called tiledbsoma in both Python and R. (https://github.com/single-cell-data/TileDB-SOMA.git).
I would be happy to add a PR if you find this interesting.
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