diff --git a/src/apify_client/clients/resource_clients/request_queue.py b/src/apify_client/clients/resource_clients/request_queue.py
index 14e57113..095fff8a 100644
--- a/src/apify_client/clients/resource_clients/request_queue.py
+++ b/src/apify_client/clients/resource_clients/request_queue.py
@@ -4,7 +4,10 @@
 import json as jsonlib
 import logging
 import math
+import re
+from base64 import b64encode
 from collections.abc import Iterable
+from hashlib import sha256
 from queue import Queue
 from typing import TYPE_CHECKING, Any, TypedDict
 
@@ -46,6 +49,29 @@ class BatchAddRequestsResult(TypedDict):
     unprocessedRequests: list[dict]
 
 
+def unique_key_to_request_id(unique_key: str, *, request_id_length: int = 15) -> str:
+    """Generate a deterministic request ID based on a unique key.
+
+    Args:
+        unique_key: The unique key to convert into a request ID.
+        request_id_length: The length of the request ID.
+
+    Returns:
+        A URL-safe, truncated request ID based on the unique key.
+    """
+    # Encode the unique key and compute its SHA-256 hash
+    hashed_key = sha256(unique_key.encode('utf-8')).digest()
+
+    # Encode the hash in base64 and decode it to get a string
+    base64_encoded = b64encode(hashed_key).decode('utf-8')
+
+    # Remove characters that are not URL-safe ('+', '/', or '=')
+    url_safe_key = re.sub(r'(\+|\/|=)', '', base64_encoded)
+
+    # Truncate the key to the desired length
+    return url_safe_key[:request_id_length]
+
+
 class RequestQueueClient(ResourceClient):
     """Sub-client for manipulating a single request queue."""
 
@@ -194,6 +220,19 @@ def get_request(self, request_id: str) -> dict | None:
 
         return None
 
+    def get_request_by_unique_key(self, unique_key: str) -> dict | None:
+        """Retrieve a request from the queue.
+
+        https://docs.apify.com/api/v2#/reference/request-queues/request/get-request
+
+        Args:
+            unique_key: Unique key of the request to retrieve.
+
+        Returns:
+            The retrieved request, or None, if it did not exist.
+        """
+        return self.get_request(unique_key_to_request_id(unique_key))
+
     def update_request(self, request: dict, *, forefront: bool | None = None) -> dict:
         """Update a request in the queue.
 
@@ -206,7 +245,7 @@ def update_request(self, request: dict, *, forefront: bool | None = None) -> dic
         Returns:
             The updated request.
         """
-        request_id = request['id']
+        request_id = request.get('id', unique_key_to_request_id(request.get('uniqueKey', '')))
 
         request_params = self._params(forefront=forefront, clientKey=self.client_key)
 
@@ -239,6 +278,16 @@ def delete_request(self, request_id: str) -> None:
             timeout_secs=_SMALL_TIMEOUT,
         )
 
+    def delete_request_by_unique_key(self, unique_key: str) -> None:
+        """Delete a request from the queue.
+
+        https://docs.apify.com/api/v2#/reference/request-queues/request/delete-request
+
+        Args:
+            unique_key: Unique key of the request to delete.
+        """
+        return self.delete_request(unique_key_to_request_id(unique_key))
+
     def prolong_request_lock(
         self,
         request_id: str,
@@ -266,6 +315,24 @@ def prolong_request_lock(
 
         return parse_date_fields(pluck_data(jsonlib.loads(response.text)))
 
+    def prolong_request_lock_by_unique_key(
+        self,
+        unique_key: str,
+        *,
+        forefront: bool | None = None,
+        lock_secs: int,
+    ) -> dict:
+        """Prolong the lock on a request.
+
+        https://docs.apify.com/api/v2#/reference/request-queues/request-lock/prolong-request-lock
+
+        Args:
+            unique_key: Unique key of the request to prolong the lock.
+            forefront: Whether to put the request in the beginning or the end of the queue after lock expires.
+            lock_secs: By how much to prolong the lock, in seconds.
+        """
+        return self.prolong_request_lock(unique_key_to_request_id(unique_key), forefront=forefront, lock_secs=lock_secs)
+
     def delete_request_lock(self, request_id: str, *, forefront: bool | None = None) -> None:
         """Delete the lock on a request.
 
@@ -284,6 +351,17 @@ def delete_request_lock(self, request_id: str, *, forefront: bool | None = None)
             timeout_secs=_SMALL_TIMEOUT,
         )
 
+    def delete_request_lock_by_unique_key(self, unique_key: str, *, forefront: bool | None = None) -> None:
+        """Delete the lock on a request.
+
+        https://docs.apify.com/api/v2#/reference/request-queues/request-lock/delete-request-lock
+
+        Args:
+            unique_key: Unique key of the request to delete the lock.
+            forefront: Whether to put the request in the beginning or the end of the queue after the lock is deleted.
+        """
+        return self.delete_request_lock(unique_key_to_request_id(unique_key), forefront=forefront)
+
     def batch_add_requests(
         self,
         requests: list[dict],
@@ -574,6 +652,19 @@ async def get_request(self, request_id: str) -> dict | None:
 
         return None
 
+    async def get_request_by_unique_key(self, unique_key: str) -> dict | None:
+        """Retrieve a request from the queue.
+
+        https://docs.apify.com/api/v2#/reference/request-queues/request/get-request
+
+        Args:
+            unique_key: Unique key of the request to retrieve.
+
+        Returns:
+            The retrieved request, or None, if it did not exist.
+        """
+        return await self.get_request(unique_key_to_request_id(unique_key))
+
     async def update_request(self, request: dict, *, forefront: bool | None = None) -> dict:
         """Update a request in the queue.
 
@@ -586,7 +677,7 @@ async def update_request(self, request: dict, *, forefront: bool | None = None)
         Returns:
             The updated request.
         """
-        request_id = request['id']
+        request_id = request.get('id', unique_key_to_request_id(request.get('uniqueKey', '')))
 
         request_params = self._params(forefront=forefront, clientKey=self.client_key)
 
@@ -617,6 +708,16 @@ async def delete_request(self, request_id: str) -> None:
             timeout_secs=_SMALL_TIMEOUT,
         )
 
+    async def delete_request_by_unique_key(self, unique_key: str) -> None:
+        """Delete a request from the queue.
+
+        https://docs.apify.com/api/v2#/reference/request-queues/request/delete-request
+
+        Args:
+            unique_key: Unique key of the request to delete.
+        """
+        return await self.delete_request(unique_key_to_request_id(unique_key))
+
     async def prolong_request_lock(
         self,
         request_id: str,
@@ -644,6 +745,26 @@ async def prolong_request_lock(
 
         return parse_date_fields(pluck_data(jsonlib.loads(response.text)))
 
+    async def prolong_request_lock_by_unique_key(
+        self,
+        unique_key: str,
+        *,
+        forefront: bool | None = None,
+        lock_secs: int,
+    ) -> dict:
+        """Prolong the lock on a request.
+
+        https://docs.apify.com/api/v2#/reference/request-queues/request-lock/prolong-request-lock
+
+        Args:
+            unique_key: Unique key of the request to prolong the lock.
+            forefront: Whether to put the request in the beginning or the end of the queue after lock expires.
+            lock_secs: By how much to prolong the lock, in seconds.
+        """
+        return await self.prolong_request_lock(
+            unique_key_to_request_id(unique_key), forefront=forefront, lock_secs=lock_secs
+        )
+
     async def delete_request_lock(
         self,
         request_id: str,
@@ -667,6 +788,17 @@ async def delete_request_lock(
             timeout_secs=_SMALL_TIMEOUT,
         )
 
+    async def delete_request_lock_by_unique_key(self, unique_key: str, *, forefront: bool | None = None) -> None:
+        """Delete the lock on a request.
+
+        https://docs.apify.com/api/v2#/reference/request-queues/request-lock/delete-request-lock
+
+        Args:
+            unique_key: Unique key of the request to delete the lock.
+            forefront: Whether to put the request in the beginning or the end of the queue after the lock is deleted.
+        """
+        return await self.delete_request_lock(unique_key_to_request_id(unique_key), forefront=forefront)
+
     async def _batch_add_requests_worker(
         self,
         queue: asyncio.Queue[Iterable[dict]],
diff --git a/tests/integration/test_request_queue.py b/tests/integration/test_request_queue.py
index 64759e47..ba1e52e1 100644
--- a/tests/integration/test_request_queue.py
+++ b/tests/integration/test_request_queue.py
@@ -2,8 +2,12 @@
 
 from typing import TYPE_CHECKING
 
+import pytest
+
 from integration.integration_test_utils import random_resource_name, random_string
 
+from apify_client.clients.resource_clients.request_queue import unique_key_to_request_id
+
 if TYPE_CHECKING:
     from apify_client import ApifyClient, ApifyClientAsync
 
@@ -113,3 +117,38 @@ async def test_request_batch_operations(self, apify_client_async: ApifyClientAsy
         assert len(requests_in_queue2['items']) == 25 - len(delete_response['processedRequests'])
 
         await queue.delete()
+
+
+def test_unique_key_to_request_id_length() -> None:
+    unique_key = 'exampleKey123'
+    request_id = unique_key_to_request_id(unique_key, request_id_length=15)
+    assert len(request_id) == 15, 'Request ID should have the correct length.'
+
+
+def test_unique_key_to_request_id_consistency() -> None:
+    unique_key = 'consistentKey'
+    request_id_1 = unique_key_to_request_id(unique_key)
+    request_id_2 = unique_key_to_request_id(unique_key)
+    assert request_id_1 == request_id_2, 'The same unique key should generate consistent request IDs.'
+
+
+@pytest.mark.parametrize(
+    ('unique_key', 'expected_request_id'),
+    [
+        ('abc', 'ungWv48BzpBQUDe'),
+        ('uniqueKey', 'xiWPs083cree7mH'),
+        ('', '47DEQpj8HBSaTIm'),
+        ('测试中文', 'lKPdJkdvw8MXEUp'),
+        ('test+/=', 'XZRQjhoG0yjfnYD'),
+    ],
+    ids=[
+        'basic_abc',
+        'keyword_uniqueKey',
+        'empty_string',
+        'non_ascii_characters',
+        'url_unsafe_characters',
+    ],
+)
+def test_unique_key_to_request_id_matches_known_values(unique_key: str, expected_request_id: str) -> None:
+    request_id = unique_key_to_request_id(unique_key)
+    assert request_id == expected_request_id, f'Unique key "{unique_key}" should produce the expected request ID.'
diff --git a/uv.lock b/uv.lock
index 70e0a525..7df1d39a 100644
--- a/uv.lock
+++ b/uv.lock
@@ -1,10 +1,10 @@
 version = 1
-revision = 3
+revision = 2
 requires-python = ">=3.10"
 
 [[package]]
 name = "apify-client"
-version = "2.0.0"
+version = "2.0.1"
 source = { editable = "." }
 dependencies = [
     { name = "apify-shared" },