interolog_prediction/infographic_for_ODin_predictor.html at main · WormBase/interolog_prediction · GitHub

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<!DOCTYPE html>
<html lang="en">
<head>
    <meta charset="UTF-8">
    <meta name="viewport" content="width=device-width, initial-scale=1.0">
    <title>Infographic: ODin Predictor powered by Alliance Orthology Data</title>
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        <!-- Header Section -->
        <header class="text-center mb-12">
            <h1 class="text-4xl md:text-5xl mb-4 text-[#FF6B6B]">ODin Predictor</h1>
            <p class="text-xl md:text-2xl font-light text-gray-600">Leveraging Alliance Orthology Data to Uncover Gene Networks</p>
        </header>

        <!-- The Challenge & The Solution -->
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            <div class="section-card">
                <h2 class="text-2xl mb-4 text-[#FF6B6B]">The Challenge: A Complex Puzzle</h2>
                <p class="mb-4">Gene and protein interactions form vast, complex networks essential for life. Experimentally mapping all these connections is incredibly slow, expensive, and difficult, leaving large gaps in our biological knowledge.</p>
                <div class="text-center text-5xl p-4">🧩</div>
            </div>
            <div class="section-card">
                <h2 class="text-2xl mb-4 text-[#60A5FA]">The Solution: "Interologs"</h2>
                <p class="mb-4">Evolution conserves function. If two genes interact in a well-studied model organism (like a fly or worm), their orthologs (evolutionary counterparts) are highly likely to interact in other species, including humans. We call these predicted interactions **interologs**.</p>
                <div class="text-center text-5xl p-4">🧬➡️🤝</div>
            </div>
        </div>

        <!-- Why Alliance of Genome Resources? -->
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                <div>
                    <div class="text-4xl mb-2">🏆</div>
                    <h3 class="text-xl mb-2">Curated Orthology</h3>
                    <p>High-quality, reliable connections between genes across multiple species.</p>
                </div>
                <div>
                    <div class="text-4xl mb-2">📚</div>
                    <h3 class="text-xl mb-2">Integrated Data</h3>
                    <p>A massive, consolidated pool of genetic and protein interaction data from trusted sources.</p>
                </div>
                <div>
                    <div class="text-4xl mb-2">🌐</div>
                    <h3 class="text-xl mb-2">Cross-Species Power</h3>
                    <p>Leverages deep knowledge from model organisms to make powerful predictions in humans.</p>
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            </div>
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            <h2 class="text-3xl text-center mb-6 text-gray-800">The Power of Prediction</h2>
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                    <h3 class="text-xl mb-2 text-[#60A5FA]">Bridging the Knowledge Gap</h3>
                    <p class="mb-4">For every known interaction, computational methods can predict many more, guiding researchers to the most promising candidates for experimental validation. This dramatically accelerates the pace of discovery.</p>
                    <p>This approach transforms a slow, needle-in-a-haystack problem into a focused, hypothesis-driven investigation.</p>
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            <h2 class="text-3xl text-center mb-8 text-gray-800">How to Use the Web App</h2>
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                    <div class="flow-step">
                        <div class="flow-number">1</div>
                        <div>
                            <h3 class="text-xl">Download Data</h3>
                            <p> One-Click data download or Visit Alliance SimpleMine, select required columns, and download the master data file.</p>
                        </div>
                    </div>
                    <div class="flow-step">
                        <div class="flow-number">2</div>
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                            <h3 class="text-xl">Upload & Input</h3>
                            <p>Upload the downloaded TSV file to our app and paste your gene IDs of interest.</p>
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                        <div class="flow-number">3</div>
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                            <h3 class="text-xl">Run Analysis</h3>
                            <p>Select your target species and interaction type, then click "Run Analysis" to start the prediction.</p>
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                        <div class="flow-number">4</div>
                        <div>
                            <h3 class="text-xl">Get Results</h3>
                            <p>Instantly receive a detailed table of predicted interactions, orthologs, and overlaps.</p>
                        </div>
                    </div>
                </div>
                <!-- Benefits Chart -->
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                     <h3 class="text-xl text-center mb-4 text-[#60A5FA]">Key Benefits of Our Tool</h3>
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             <h2 class="text-3xl font-bold mb-2">Accelerate Your Research Today</h2>
             <p class="text-lg font-light">Turn complex data into actionable hypotheses with our secure, private, and powerful client-side tool.</p>
        </div>

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