See more details here.
Unless nvidia's shader cache is disabled, all emulators that use the latest version of parallel-rdp will crash after some time after booting any game.
Happens on both simple64 and ares when using the latest version of those emulators. (in contrast, version v138 of the ares emulator works as intended)
Disabling the shader cache seems to fix the issue.
(UPD. If that helps, the GPU I'm using is Nvidia GeForce GT 1030)