diff --git a/src/pruna/algorithms/moe_kernel_tuner.py b/src/pruna/algorithms/moe_kernel_tuner.py
index 99929f81..f4a9f44b 100644
--- a/src/pruna/algorithms/moe_kernel_tuner.py
+++ b/src/pruna/algorithms/moe_kernel_tuner.py
@@ -130,6 +130,18 @@ def get_hyperparameters(self) -> list:
                 default_value=8,
                 meta={"desc": "Maximum (log) block size for tiling through intermediate dimension."},
             ),
+            OrdinalHyperparameter(
+                "block_quant_shape_n",
+                sequence=[32, 64, 128, 256, 512, 1024, 2048, 4096, None],
+                default_value=None,
+                meta={"desc": "Block size for quantization through input dimension."},
+            ),
+            OrdinalHyperparameter(
+                "block_quant_shape_k",
+                sequence=[32, 64, 128, 256, 512, 1024, 2048, 4096, None],
+                default_value=None,
+                meta={"desc": "Block size for quantization through intermediate dimension."},
+            ),
         ]
 
     def model_check_fn(self, model: Any) -> bool:
@@ -178,6 +190,11 @@ def _apply(self, model: Any, smash_config: SmashConfigPrefixWrapper) -> Any:
         model_config = getattr(model, "config", None)
         if model_config is None:
             raise ValueError(f"Model {model.__class__.__name__} has no config.")
+        # Multimodal MoE (e.g. Qwen3_5MoeForConditionalGeneration): MoE parameters live on text_config.
+        if getattr(model_config, "num_experts", None) is None:
+            text_cfg = getattr(model_config, "text_config", None)
+            if text_cfg is not None and getattr(text_cfg, "num_experts", None) is not None:
+                model_config = text_cfg
 
         tensor_parallel_size = int(smash_config["tensor_parallel_size"])
         if model.__class__.__name__ == "HunyuanImage3ForCausalMM":
@@ -194,6 +211,15 @@ def _apply(self, model: Any, smash_config: SmashConfigPrefixWrapper) -> Any:
         dtype = torch.bfloat16 if dtype == "bfloat16" else torch.float16
         use_fp8_w8a8 = smash_config["weight_dtype"] == "fp8_w8a8"
         use_int8_w8a16 = smash_config["weight_dtype"] == "int8_w8a16"
+        block_quant_shape = None
+        if (
+            smash_config["block_quant_shape_n"] is not None
+            and smash_config["block_quant_shape_k"] is not None
+        ):
+            block_quant_shape = [
+                smash_config["block_quant_shape_n"],
+                smash_config["block_quant_shape_k"],
+            ]
 
         # (iii) Tune the kernel over a range of batch sizes (single GPU per Ray worker).
         batch_sizes = [1, 2, 4, 8, 16, 32, 64, 128, 256, 512, 1024, 2048, 4096, 8192]
@@ -206,6 +232,22 @@ def _apply(self, model: Any, smash_config: SmashConfigPrefixWrapper) -> Any:
 
         ray.init(ignore_reinit_error=True)
         search_space = get_configs_compute_bound(smash_config)
+
+        # Remove configs incompatible with block quantisation constraints:
+        # - BLOCK_SIZE_K must be divisible by block_quant_shape_k
+        # - BLOCK_SIZE_N must be divisible by block_quant_shape_n
+        if (
+            smash_config["block_quant_shape_n"] is not None
+            and smash_config["block_quant_shape_k"] is not None
+            and use_fp8_w8a8
+        ):
+            search_space = [
+                cfg
+                for cfg in search_space
+                if cfg["BLOCK_SIZE_K"] % smash_config["block_quant_shape_k"] == 0
+                and cfg["BLOCK_SIZE_N"] % smash_config["block_quant_shape_n"] == 0
+            ]
+
         pruna_logger.info(f"Start tuning over {len(search_space)} configurations...")
 
         start = time.time()
@@ -226,7 +268,7 @@ def _apply(self, model: Any, smash_config: SmashConfigPrefixWrapper) -> Any:
                     use_fp8_w8a8,
                     use_int8_w8a16,
                     search_space,
-                    None,
+                    block_quant_shape,
                     False,
                     imported_packages,
                     0,  # fixed seed for reproducibility
@@ -266,7 +308,7 @@ def _apply(self, model: Any, smash_config: SmashConfigPrefixWrapper) -> Any:
             dtype,
             use_fp8_w8a8,
             use_int8_w8a16,
-            None,
+            block_quant_shape,
             smash_config["path_to_huggingface_hub_cache"],
             smash_config["path_to_vllm_cache"],
             imported_packages,
diff --git a/src/pruna/engine/model_checks.py b/src/pruna/engine/model_checks.py
index fa5fb763..2f15a4eb 100644
--- a/src/pruna/engine/model_checks.py
+++ b/src/pruna/engine/model_checks.py
@@ -109,7 +109,9 @@ def is_moe_lm(model: Any) -> bool:
     """
     Check if the model is a MoE LM.
 
-    Currently all MoE LMs are based on Mixtral in transformers.
+    Detects MoE via ``config.num_experts`` (e.g. Mixtral, Qwen-MoE text-only)
+    or via nested ``config.text_config.num_experts`` (e.g. multimodal
+    ``*ForConditionalGeneration`` wrappers).
 
     Parameters
     ----------
@@ -121,7 +123,13 @@ def is_moe_lm(model: Any) -> bool:
     bool
         True if the model is a MoE LM, False otherwise.
     """
-    return hasattr(getattr(model, "config", None), "num_experts")
+    config = getattr(model, "config", None)
+    if config is None:
+        return False
+    if getattr(config, "num_experts", None) is not None:
+        return True
+    text_cfg = getattr(config, "text_config", None)
+    return text_cfg is not None and getattr(text_cfg, "num_experts", None) is not None
 
 
 def is_transformers_pipeline_with_causal_lm(model: Any) -> bool: