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DESCRIPTION
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Package: PERSEO
Type: Package
Title: Model-Aware Differential Expression for Omics Data
Version: 1.0.0
Authors@R: c(
person("Sergio", "Olmos-Piñero",
email = "solmos97@gmail.com",
role = c("aut", "cre")),
person("Val", "Fenández-Lanza",
email = "valVF@gmail.com",
role = "aut")
)
Description: Automated model selection and differential expression analysis for
high-dimensional omics data using GAMLSS (Generalized Additive Models for
Location, Scale and Shape). Supports overdispersed, skewed, or otherwise
non-standard distributions by testing multiple GAMLSS families per feature
with strict transformations, common masking, and Jacobian correction for
fair model comparison. Enables accurate inference across heterogeneous
feature types (counts, proportions, positive continuous, real-valued).
License: GPL-3
Encoding: UTF-8
LazyData: true
Depends:
R (>= 4.2.0)
Imports:
gamlss (>= 5.4.0),
gamlss.dist (>= 6.0.0),
dplyr (>= 1.0.0),
tibble (>= 3.0.0),
rlang (>= 1.0.0),
stats,
utils,
progressr
Suggests:
testthat (>= 3.0.0),
future (>= 1.32.0),
future.apply (>= 1.11.0),
cli (>= 3.6.0),
devtools,
covr,
knitr,
rmarkdown
RoxygenNote: 7.3.3
VignetteBuilder: knitr
URL: https://github.com/OPSergio/Perseo
BugReports: https://github.com/OPSergio/Perseo/issues