diff --git a/README.md b/README.md
index 9967805..a5301b6 100644
--- a/README.md
+++ b/README.md
@@ -23,40 +23,16 @@ There is a series of detailed tutorials for *PolyConf* in the folder [polyconf_e
 
 ## Quick and dirty installation
 
-From your home directory, clone *PolyConstruct* from this repository:
-
-```bash
-cd ~
-git clone https://github.com/OMaraLab/polyconstruct.git
-```
-
-Then navigate to `~/polyconstruct`
-
-```bash
-cd polyconstruct
-```
-
-Create a python environment and setup *PolyConstruct*:
+Create and activate a new python environment:
 
 ```bash
 conda create --name polyconstruct python=3.10
 conda activate polyconstruct
-
-pip install -r requirements.txt
 ```
 
-Then, build the *PolyTop*, *PolyConf* and *PolyBuild* packages:
+Install dependencies and *PolyConstruct*:
 
 ```bash
-cd polytop
-
-pip install -e .
-
-cd ../polyconf
-
-pip install -e .
-
-cd ../polybuild
-
-pip install -e .
+pip install "polyconstruct@git+https://github.com/OMaraLab/polyconstruct.git"
 ```
+
diff --git a/pyproject.toml b/pyproject.toml
index 6818e75..d51962b 100644
--- a/pyproject.toml
+++ b/pyproject.toml
@@ -13,13 +13,20 @@ license = { text = "MIT License" }
 
 # Dependencies required for your project
 dependencies = [
-    "numpy",
-    "mdanalysis",
-    "click",
-    "py3Dmol",
-    "rdkit",
+    "numpy==2.2.6",
+    "MDAnalysis==2.9.0",
+    "click==8.3.0",
+    "py3Dmol==2.5.2",
+    "rdkit==2025.3.6",
+    "networkx==3.4.2",
+    "pandas==2.3.2",
+    "tqdm==4.67.1"
 ]
 
-[tool.setuptools.packages.find]
-where = ["."]
-include = ["*"]
\ No newline at end of file
+[tool.setuptools]
+packages = ["polybuild", "polybuild.polybuild", "polyconf", "polyconf.polyconf", "polytop", "polytop.polytop"]
+
+[tool.setuptools.package-dir]
+polybuild.polybuild = "polybuild"
+polyconf.polyconf = "polyconf"
+polytop.polytop = "polytop"
\ No newline at end of file
diff --git a/requirements.txt b/requirements.txt
deleted file mode 100644
index 1c5ad7e..0000000
--- a/requirements.txt
+++ /dev/null
@@ -1,13 +0,0 @@
-IPython
-jupyter
-nbconvert
-nbformat
-pytest
-rdkit
-py3Dmol
-numpy
-mdanalysis
-click
-py3Dmol
-networkx
-tqdm