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From the publication and vignette here, it's unclear what is the expected performance of the model. For instance, in BasicExample.ipynb your model assigns weight to each explanatory variable. In the publication, the top 100 genes are selected for further analysis (how? top betas? What parameters yielded those results?).
Some clearer explanations and examples on how you would recommend tuning parameters and training the model would be helpful to include in this repo. For scientific purposes, it would also help in reproducing results from the publication.
Thanks
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