diff --git a/ozone-framework-python-server/requirements.txt b/ozone-framework-python-server/requirements.txt
index 74d3b911..e5e90d32 100644
--- a/ozone-framework-python-server/requirements.txt
+++ b/ozone-framework-python-server/requirements.txt
@@ -28,7 +28,7 @@ pyparsing==2.4.1.1
 python-cas==1.4.0
 pytz==2019.1
 requests==2.22.0
-setuptools==41.6.0
+setuptools==65.5.1
 simplejson==3.16.0
 six==1.12.0
 snowballstemmer==1.9.0