diff --git a/src-tauri/src/types.rs b/src-tauri/src/types.rs
index 1574b5363..5a1e62f33 100644
--- a/src-tauri/src/types.rs
+++ b/src-tauri/src/types.rs
@@ -267,6 +267,8 @@ pub(crate) struct AppSettings {
         rename = "composerReasoningShortcut"
     )]
     pub(crate) composer_reasoning_shortcut: Option<String>,
+    #[serde(default = "default_interrupt_shortcut", rename = "interruptShortcut")]
+    pub(crate) interrupt_shortcut: Option<String>,
     #[serde(default = "default_new_agent_shortcut", rename = "newAgentShortcut")]
     pub(crate) new_agent_shortcut: Option<String>,
     #[serde(
@@ -446,6 +448,10 @@ fn default_composer_reasoning_shortcut() -> Option<String> {
     Some("cmd+shift+r".to_string())
 }
 
+fn default_interrupt_shortcut() -> Option<String> {
+    Some("ctrl+c".to_string())
+}
+
 fn default_new_agent_shortcut() -> Option<String> {
     Some("cmd+n".to_string())
 }
@@ -569,6 +575,7 @@ impl Default for AppSettings {
             composer_model_shortcut: default_composer_model_shortcut(),
             composer_access_shortcut: default_composer_access_shortcut(),
             composer_reasoning_shortcut: default_composer_reasoning_shortcut(),
+            interrupt_shortcut: default_interrupt_shortcut(),
             new_agent_shortcut: default_new_agent_shortcut(),
             new_worktree_agent_shortcut: default_new_worktree_agent_shortcut(),
             new_clone_agent_shortcut: default_new_clone_agent_shortcut(),
@@ -635,6 +642,7 @@ mod tests {
             settings.composer_reasoning_shortcut.as_deref(),
             Some("cmd+shift+r")
         );
+        assert_eq!(settings.interrupt_shortcut.as_deref(), Some("ctrl+c"));
         assert_eq!(
             settings.toggle_debug_panel_shortcut.as_deref(),
             Some("cmd+shift+d")
diff --git a/src/App.tsx b/src/App.tsx
index deab2e6ef..ef21265bc 100644
--- a/src/App.tsx
+++ b/src/App.tsx
@@ -78,6 +78,7 @@ import { useAppMenuEvents } from "./features/app/hooks/useAppMenuEvents";
 import { useWorkspaceActions } from "./features/app/hooks/useWorkspaceActions";
 import { useWorkspaceCycling } from "./features/app/hooks/useWorkspaceCycling";
 import { useThreadRows } from "./features/app/hooks/useThreadRows";
+import { useInterruptShortcut } from "./features/app/hooks/useInterruptShortcut";
 import { useCopyThread } from "./features/threads/hooks/useCopyThread";
 import { useTerminalController } from "./features/terminal/hooks/useTerminalController";
 import { useGitCommitController } from "./features/app/hooks/useGitCommitController";
@@ -1118,6 +1119,14 @@ function MainApp() {
     onDropPaths: handleDropWorkspacePaths,
   });
 
+  useInterruptShortcut({
+    isEnabled: canInterrupt,
+    shortcut: appSettings.interruptShortcut,
+    onTrigger: () => {
+      void interruptTurn();
+    },
+  });
+
   const {
     handleSelectPullRequest,
     resetPullRequestSelection,
diff --git a/src/features/app/hooks/useInterruptShortcut.ts b/src/features/app/hooks/useInterruptShortcut.ts
new file mode 100644
index 000000000..5255f8a21
--- /dev/null
+++ b/src/features/app/hooks/useInterruptShortcut.ts
@@ -0,0 +1,32 @@
+import { useEffect } from "react";
+import { matchesShortcut } from "../../../utils/shortcuts";
+
+type UseInterruptShortcutOptions = {
+  isEnabled: boolean;
+  shortcut: string | null;
+  onTrigger: () => void | Promise<void>;
+};
+
+export function useInterruptShortcut({
+  isEnabled,
+  shortcut,
+  onTrigger,
+}: UseInterruptShortcutOptions) {
+  useEffect(() => {
+    if (!isEnabled || !shortcut) {
+      return;
+    }
+    const handleKeyDown = (event: KeyboardEvent) => {
+      if (event.repeat) {
+        return;
+      }
+      if (!matchesShortcut(event, shortcut)) {
+        return;
+      }
+      event.preventDefault();
+      void onTrigger();
+    };
+    window.addEventListener("keydown", handleKeyDown);
+    return () => window.removeEventListener("keydown", handleKeyDown);
+  }, [isEnabled, onTrigger, shortcut]);
+}
diff --git a/src/features/settings/components/SettingsView.test.tsx b/src/features/settings/components/SettingsView.test.tsx
index 7f0e32769..4e1562da6 100644
--- a/src/features/settings/components/SettingsView.test.tsx
+++ b/src/features/settings/components/SettingsView.test.tsx
@@ -26,6 +26,7 @@ const baseSettings: AppSettings = {
   composerModelShortcut: null,
   composerAccessShortcut: null,
   composerReasoningShortcut: null,
+  interruptShortcut: null,
   newAgentShortcut: null,
   newWorktreeAgentShortcut: null,
   newCloneAgentShortcut: null,
diff --git a/src/features/settings/components/SettingsView.tsx b/src/features/settings/components/SettingsView.tsx
index 93265ee68..e9d4b1876 100644
--- a/src/features/settings/components/SettingsView.tsx
+++ b/src/features/settings/components/SettingsView.tsx
@@ -134,6 +134,7 @@ type ShortcutSettingKey =
   | "composerModelShortcut"
   | "composerAccessShortcut"
   | "composerReasoningShortcut"
+  | "interruptShortcut"
   | "newAgentShortcut"
   | "newWorktreeAgentShortcut"
   | "newCloneAgentShortcut"
@@ -149,6 +150,7 @@ type ShortcutDraftKey =
   | "model"
   | "access"
   | "reasoning"
+  | "interrupt"
   | "newAgent"
   | "newWorktreeAgent"
   | "newCloneAgent"
@@ -165,6 +167,7 @@ const shortcutDraftKeyBySetting: Record<ShortcutSettingKey, ShortcutDraftKey> =
   composerModelShortcut: "model",
   composerAccessShortcut: "access",
   composerReasoningShortcut: "reasoning",
+  interruptShortcut: "interrupt",
   newAgentShortcut: "newAgent",
   newWorktreeAgentShortcut: "newWorktreeAgent",
   newCloneAgentShortcut: "newCloneAgent",
@@ -230,6 +233,7 @@ export function SettingsView({
     model: appSettings.composerModelShortcut ?? "",
     access: appSettings.composerAccessShortcut ?? "",
     reasoning: appSettings.composerReasoningShortcut ?? "",
+    interrupt: appSettings.interruptShortcut ?? "",
     newAgent: appSettings.newAgentShortcut ?? "",
     newWorktreeAgent: appSettings.newWorktreeAgentShortcut ?? "",
     newCloneAgent: appSettings.newCloneAgentShortcut ?? "",
@@ -317,6 +321,7 @@ export function SettingsView({
       model: appSettings.composerModelShortcut ?? "",
       access: appSettings.composerAccessShortcut ?? "",
       reasoning: appSettings.composerReasoningShortcut ?? "",
+      interrupt: appSettings.interruptShortcut ?? "",
       newAgent: appSettings.newAgentShortcut ?? "",
       newWorktreeAgent: appSettings.newWorktreeAgentShortcut ?? "",
       newCloneAgent: appSettings.newCloneAgentShortcut ?? "",
@@ -333,6 +338,7 @@ export function SettingsView({
     appSettings.composerAccessShortcut,
     appSettings.composerModelShortcut,
     appSettings.composerReasoningShortcut,
+    appSettings.interruptShortcut,
     appSettings.newAgentShortcut,
     appSettings.newWorktreeAgentShortcut,
     appSettings.newCloneAgentShortcut,
@@ -1755,6 +1761,30 @@ export function SettingsView({
                     Default: {formatShortcut("cmd+shift+r")}
                   </div>
                 </div>
+                <div className="settings-field">
+                  <div className="settings-field-label">Stop active run</div>
+                  <div className="settings-field-row">
+                    <input
+                      className="settings-input settings-input--shortcut"
+                      value={formatShortcut(shortcutDrafts.interrupt)}
+                      onKeyDown={(event) =>
+                        handleShortcutKeyDown(event, "interruptShortcut")
+                      }
+                      placeholder="Type shortcut"
+                      readOnly
+                    />
+                    <button
+                      type="button"
+                      className="ghost settings-button-compact"
+                      onClick={() => void updateShortcut("interruptShortcut", null)}
+                    >
+                      Clear
+                    </button>
+                  </div>
+                  <div className="settings-help">
+                    Default: {formatShortcut("ctrl+c")}
+                  </div>
+                </div>
                 <div className="settings-divider" />
                 <div className="settings-subsection-title">Panels</div>
                 <div className="settings-subsection-subtitle">
diff --git a/src/features/settings/hooks/useAppSettings.ts b/src/features/settings/hooks/useAppSettings.ts
index 2448b4e02..10a2102fb 100644
--- a/src/features/settings/hooks/useAppSettings.ts
+++ b/src/features/settings/hooks/useAppSettings.ts
@@ -21,6 +21,7 @@ const defaultSettings: AppSettings = {
   composerModelShortcut: "cmd+shift+m",
   composerAccessShortcut: "cmd+shift+a",
   composerReasoningShortcut: "cmd+shift+r",
+  interruptShortcut: "ctrl+c",
   newAgentShortcut: "cmd+n",
   newWorktreeAgentShortcut: "cmd+shift+n",
   newCloneAgentShortcut: "cmd+alt+n",
diff --git a/src/types.ts b/src/types.ts
index 8c0cdbff9..6fe9a0790 100644
--- a/src/types.ts
+++ b/src/types.ts
@@ -97,6 +97,7 @@ export type AppSettings = {
   composerModelShortcut: string | null;
   composerAccessShortcut: string | null;
   composerReasoningShortcut: string | null;
+  interruptShortcut: string | null;
   newAgentShortcut: string | null;
   newWorktreeAgentShortcut: string | null;
   newCloneAgentShortcut: string | null;