PSI statistic

[zeeev]

I would like to propose the addition of a Percent Spliced-In (PSI) calculation module to FLAIR. PSI is a widely used metric in alternative splicing analysis, representing the proportion of transcripts that include a particular exon. Incorporating PSI calculation into FLAIR would enhance its utility.

[cafelton]

There is some implementation of this in FLAIR diffsplice, but the number of splicing events diffsplice handles is limited. I've gotten a few comments on this recently and do plan to expand it.
I think that based on this comment, we can also modify diffsplice to explicitly output PSI tables as well as alternatively spliced events.

[zeeev]

Thanks. Just getting started, but thought I'd mention it, as I keep seeing it in my literature review of cancer.

[diekhans]

Hi Zev!! This is a great suggestion! We will add it to our enhancement list. Mark Zev Kronenberg ***@***.***> writes:

…

I would like to propose the addition of a Percent Spliced-In (PSI) calculation module to FLAIR. PSI is a widely used metric in alternative splicing analysis, representing the proportion of transcripts that include a particular exon. Incorporating PSI calculation into FLAIR would enhance its utility. -- Reply to this email directly or view it on GitHub: #480 You are receiving this because you are subscribed to this thread. Message ID: ***@***.***>

[zeeev]

Thanks to both of you.