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Description
- Aim: benchmark the quality of missing data imputation and find if imputing data is necessary for decision-making based on the metabolomics data.
2. Scheme: https://viewer.diagrams.net/?page-id=_Gg_AfVaFpc6PrHJ8jsU&highlight=0000ff&edit=_blank&layers=1&nav=1&page-id=_Gg_AfVaFpc6PrHJ8jsU#G1z9yDcNV2doGwIQaU7gxAmNQtFy5LXXCc - Types of missing values.
- Considered imputation methods.
- "Safe imputation" https://github.com/michbur/metabolomics-missing-value-imputation/blob/main/functions/imputing.R#L68
- Problems:
7. How to measure the impact on modeling?
8. Is there a single measure incorporating the quality of imputation and the speed of the imputation?
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